Job Description

We're here for one reason and one reason only - to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We've made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. **Job Description** We are seeking a highly motivated and experienced Scientist to join our team in the field of cellular biology and lipid nanoparticle research. The successful candidate will be responsible for designing, executing, and analyzing experiments related to the development and characterization of lipid nanoparticle-based and other delivery systems for therapeutic applications. **Responsibilities:** + Design and conduct experiments to develop and optimize lipid nanoparticle formulations for the delivery of nucleic acids (e.g. siRNA, mRNA) or small molecule drugs. + Perform molecular biology techniques such as mRNA synthesis and processing, gene expression analysis (e.g. qPCR, flow cytometry), and cell-based assays to evaluate the efficacy and mechanisms of action of lipid nanoparticle formulations. + Characterize lipid nanoparticles using various analytical techniques. The assays may include dynamic light scattering (DLS), zeta potential measurements, and transmission electron microscopy (TEM). + Develop and optimize protocols for the synthesis, purification, and analysis of lipid nanoparticles. + Maintain detailed and accurate records of experimental procedures, data, and results in laboratory notebooks and electronic databases. + Analyze and interpret experimental data and present findings in team meetings and scientific conferences. + Collaborate with cross-functional teams, including chemists, biologists, and computational scientists, to advance the development of lipid nanoparticle-based therapeutics. + Contribute to the preparation of scientific reports, manuscripts, and patent applications. + Ensure compliance with laboratory safety protocols, good laboratory practices (GLP), and regulatory guidelines. **Basic Qualifications:** + PhD degree in Molecular Biology, Biochemistry, Bioengineering, or a related field, with a strong background in lipid nanoparticle research and drug delivery systems OR + Master's degree in molecular biology, Biochemistry, Bioengineering, or a related field, with a 4+ years of experience in lipid nanoparticle research and drug delivery systems OR + Bachelor's degree in molecular biology, Biochemistry, Bioengineering, or a related field, with a 6+ years of experience in lipid nanoparticle research and drug delivery systems **Preferred Qualifications:** + PhD degree in Molecular Biology, Biochemistry, Bioengineering, or a related field, with a strong background in lipid nanoparticle research and drug delivery systems + Extensive hands-on experience with molecular biology techniques, including nucleic acid manipulation, gene expression analysis, and cell-based assays. + Proficiency in lipid nanoparticle formulation, characterization, and analysis techniques. Knowledge in techniques such as DLS, zeta potential measurements, and TEM would be a plus. + Excellent analytical and problem-solving skills, with the ability to design and execute well-controlled experiments. + Strong written and verbal communication skills, with the ability to present complex scientific data effectively. + Ability to work independently and as part of a collaborative team in a dynamic research environment. + Familiarity with GLP, regulatory guidelines, and safety protocols. + Research experience in the field of lipid nanoparticle-based drug delivery or related areas. + Experience with in vivo studies and animal models relevant to therapeutic applications. + Knowledge of bioinformatics tools and computational approaches for data analysis. + Familiarity with intellectual property and patent writing. The salary range for this position is: $146,540.00 - $189,640.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit . Sign up to follow @KitePharma on Twitter at . **For jobs in the United States:** Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' ( poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT ( YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION ( Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. **For Current Kite Pharma Employees and Contractors:** Please apply via the Internal Career Opportunities portal in Workday. **Change The World With Us** Everyone at Kite is grounded by one common goal - curing cancer. Every day, we aim to establish a direct line between that purpose and our day-to-day work. We are creating Kite together, with the recognition that the best teams are built by the best people. We maintain an attitude of curiosity, and creativity with each challenge as we develop a new market for cancer therapies. We appreciate and respect one another, and most importantly, we don't take success for granted. While we've come a long way to make what others viewed as impossible, possible, we know one thing is certain. Today is just the beginning.

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